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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC63
All Species:
32.42
Human Site:
S585
Identified Species:
54.87
UniProt:
Q9UGP8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGP8
NP_009145.1
760
87997
S585
E
E
E
T
N
R
D
S
Q
S
E
K
D
D
G
Chimpanzee
Pan troglodytes
XP_001148185
760
87976
S585
E
E
E
T
N
R
D
S
Q
S
E
K
D
D
G
Rhesus Macaque
Macaca mulatta
XP_001091991
689
79874
V539
L
K
K
K
P
T
P
V
L
L
P
Q
S
K
Q
Dog
Lupus familis
XP_532252
850
96553
S675
E
E
E
T
N
R
E
S
Q
S
E
K
D
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHE0
760
87823
S585
E
E
E
T
N
R
D
S
Q
S
E
K
E
D
G
Rat
Rattus norvegicus
NP_001101107
727
83574
S574
E
D
I
S
D
K
G
S
D
S
E
E
E
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511532
775
89598
S600
E
E
E
A
N
R
D
S
Q
S
D
K
D
D
G
Chicken
Gallus gallus
XP_419802
759
87965
S584
E
E
E
T
N
R
D
S
Q
S
E
K
D
D
G
Frog
Xenopus laevis
NP_001088542
754
87189
S583
D
E
D
Q
N
R
D
S
Q
S
D
G
S
D
K
Zebra Danio
Brachydanio rerio
XP_002666271
754
86861
S582
E
A
E
G
N
K
D
S
P
S
E
R
D
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648111
753
85835
G586
S
D
V
E
S
A
A
G
S
G
S
E
D
E
E
Honey Bee
Apis mellifera
XP_395961
751
87148
D578
E
D
K
I
E
K
D
D
S
D
V
D
S
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793617
800
91710
V586
A
K
P
L
L
R
T
V
D
Q
D
D
D
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14906
663
75326
C514
T
K
R
R
G
S
W
C
C
L
V
S
S
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
89.3
88.3
N.A.
96.1
91.8
N.A.
86.8
91.5
83.4
72.3
N.A.
44
42.3
N.A.
40.8
Protein Similarity:
100
99.8
89.8
89.1
N.A.
98.5
94.2
N.A.
91.8
95.7
91.8
84.7
N.A.
63.6
62.3
N.A.
59
P-Site Identity:
100
100
0
93.3
N.A.
93.3
26.6
N.A.
86.6
100
53.3
60
N.A.
6.6
20
N.A.
20
P-Site Similarity:
100
100
20
100
N.A.
100
73.3
N.A.
93.3
100
73.3
73.3
N.A.
33.3
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
8
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% C
% Asp:
8
22
8
0
8
0
58
8
15
8
22
15
58
65
0
% D
% Glu:
65
50
50
8
8
0
8
0
0
0
50
15
15
15
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
8
8
0
8
0
8
0
0
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
22
15
8
0
22
0
0
0
0
0
43
0
8
15
% K
% Leu:
8
0
0
8
8
0
0
0
8
15
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
58
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
8
0
8
0
8
0
8
0
8
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
50
8
0
8
0
8
8
% Q
% Arg:
0
0
8
8
0
58
0
0
0
0
0
8
0
0
8
% R
% Ser:
8
0
0
8
8
8
0
65
15
65
8
8
29
0
0
% S
% Thr:
8
0
0
36
0
8
8
0
0
0
0
0
0
0
8
% T
% Val:
0
0
8
0
0
0
0
15
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _